Welcome to Yuzaki Lab
    Yuzaki Lab's (Department of Neurophysiology, Keio University School of Medicine) research theme is to elucidate "how neural activity and environmental changes induce memory and learning,、, 、and how they change the neural network itself ."。For details please Click here.
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We await the participation of motivated indivisuals。We will vigorously nurture young researchers who will lead the future of basic science.。
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Efficient method of differentiating neural progenitor cells in the common marmoset ES (PLoS One)2012.11.18

Shimada H, Okada Y, Ibata K, Ebise H, Ota S, Tomioka I, Nomura T, Maeda T, Kohda K,Yuzaki M, Sasaki E, Nakamura M, Okano H. Efficient Derivation of Multipotent Neural Stem/Progenitor Cells from Non-Human Primate Embryonic Stem Cells. PLoS One, 7(11):e49469, 2012.

It is the result of joint research with Ken Okano。

To induce the formation of presynaptic projection-Cbln1-GluD2 signaling process real-time visualization of synapse formation (Neuron)2012.11.8

Ito-Ishida A, Miyazaki T, Miura E, Matsuda K, Watanabe M, Them so M *, Okabe S*. Presynaptically released Cbln1 induces dynamic axonal structural changes by interacting with GluD2 during cerebellar synapse formation. Neuron., 76:549-564, 2012. (*co-corresponding author).

After MD, Ph.D. obtained in our department、At the University of Tokyo Okabe Research is the thesis of Mr. Ishida who was SPD (currently studying)。It is the result of joint research with the University of Tokyo Ken Okabe Ken Watanabe Hokkaido。

Examination of mice deficient-GluD2 gait analysis in a mouse model of cerebellar ataxia mouse (PLoS One)2012.10.20

Takeuchi E, Sato Y, Miura E, Yamaura H, Yuzaki M, Yanagihara D. Characteristics of Gait ataxia in δ2 Glutamate Receptor Mutant Mice, ho15J. PLoS One. 2012;7(10):e47553.

Results of joint research with the University of Tokyo Ken Yanagihara - is Ken Yanagihara Takeuchi's doctoral dissertation of。

Study of motor learning and relationship-GluD2 cerebellar LTD gives you a hint (Invited review, Neural Networks)2012.6.19

Yuzaki M. Cerebellar LTD vs. motor learning— lessons learned from studying GluD2 Neural Networks, in press.

This objection to a recent research report that the "cerebellar LTD has no relationship with the motor learning."。Neural Networks special issue "Computations, Neural Circuits, Behavior and Anatomy of the Cerebellum」に掲載。

Development of gene transfer is controlled to selectively and cerebellar Purkinje cells using in utero electroporation (Eur J Neurosci)2012.6.19

Nishiyama J, Hayashi, Y, Nomura T, Miura E, Kakegawa W, Yuzaki M. Selective and regulated gene expression in murine Purkinje cells by in utero electroporation. Eur J Neurosci, 36: 2867-2876, 2012.

And Nishiyama Mr. studying in Duke、Hayashi's Assistant Professor of co-first is the author of the paper。

Required for cerebellar LTD happen to be dephosphorylated TARP (Eur J Neurosci)2012.1.6

Nomura T, Kakegawa W, Matsuda S, Kohda K, Nishiyama J, Takahashi T, Yuzaki M. Cerebellar long-term depression requires dephosphorylation of TARP in Purkinje cells. Eur J Neurosci, 35:402-410, 2012.

Graduate students is the Nomura-kun of the thesis。

NMDA receptor activation by controlling the LTD to produce PIP2 in synaptic (Neuron)2012.1.6

Unokai T, Matsuda S, Kakegawa W, UT, Kohda K, Suzuki A, Funakoshi Y, Hasegawa H, Them so M *, Kanaho Y. NMDA receptor-mediated PIP5K activation to produce PI(4,5)P2 is essential for AMPA receptor endocytosis during LTD. Neuron., 73: 135-148, 2012.(*co-corresponding author)
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In the results of joint research with the University of Tsukuba KimuTamotsuken、Unoki kun had come to Keio from KimuTamotsuken (graduate student)、3 people of Mazda Kakegawa lecturer is the first author。Unoki we are a degree in this paper、He was awarded the "Best Paper Award" at the University of Tsukuba。