Pitch contest for startups (S2S Japan: Science to Startup)Yuzaki was selected as a finalist for。11A one-day symposium attended by domestic and international investors, pharmaceutical companies, etc. will be held on April 12th at Tokyo Midtown Yaesu Conference.。I will be on stage as a top batter.。Pre-registration (free)is required。Other finalists are:：

Michisuke Yuzaki, MD, Ph.D. (Keio University) / Bio2Q) “BiNEs reconnecting neural synapses："A new therapeutic platform expanding from Parkinson's disease"
Gen Matsumoto, Ph.D. (Osaka Public University) “New therapeutic strategies for neurodegenerative diseases”：Toward a dementia-free future with oral medications.”
Tomohiro Miyai, D.Sc. (RIKEN Center for Biomedical Sciences) “Development of topical cyclic peptide for atopic dermatitis”
Shunsuke Ito, Ph.D., MBA (HiLung Co., Ltd.) “Development of best-in-class inhaled LPA1 antagonist HL001, a candidate for IPF treatment”
Daisuke Morishita, Ph.D. (SODAI Therapeutics Inc.) “NativeSense ADC™: Targeting Glycosaminoglycans through pHConditional Binding for Heterogeneous Tumors」
Tadashi Kato, MD, Ph.D. (Juntendo University) “mPTP inhibitors for bipolar disorder”：A new approach targeting mitochondria.”

The 49th Annual Meeting of the Japanese Society of Molecular Biology and the 99th Annual Meeting of the Japanese Society of Biochemistry (BMB2026 Contract Meeting)(Noboru Mizushima, Chairman of Hitoshi Kurumizaka University) December 4th 9：00－11：00Yuzaki will give a lecture at the conference planning symposium “From basic research to disease control” to be held in。Other speakers are Keiichi Nakayama (Tokyo University of Science)、Kenya Honda (Keio University)、My name is Motoko Yanagita (Kyoto University).。

5th Keio University WPI-Bio2Q International Symposiumwill be held at Keio University from December 9th to 10th. Kitasato Auditoriumwill be held in。In this symposium、“Wiring the Body: The theme is “Brain–Organ–Microbiome Networks”、Focus on the nervous system、We invite cutting-edge researchers from Japan and abroad who are working to elucidate the linkage mechanism between the microbiome and multiple organs.。brain and peripheral organs、immune system、How the intestinal flora exchange information、Regarding whether it affects health or disease、discuss from multiple angles。Pre-registration (free)is required, so please apply as soon as possible!

Stanford University ChEM-H / The symposium will be held from December 11th to 12th at the Neuro research complex.Brain aging and degeneration: Grand challenges and new paradigmsYuzaki is scheduled to give a lecture at。

176th Brain Club Structural Biology Colloquium, Held on October 29th in collaboration with Bio2Q。Speaker: Bordeaux University Interdisciplinary Institute
by Jonathan Elegheert, Team Leader for Neuroscience、The title of the presentation was "Understanding synaptic organization through structural biology and protein engineering"。About the structure and function of AMPA-type glutamate receptors that convey rapid neurotransmission in our brains、We talked about the latest knowledge。The function of AMPA receptors is regulated by the simultaneous binding of various molecules.、Structure cannot be determined in many cases due to low binding affinity。Dr. Elegheert also talked about new techniques to solve this problem.。

International leading research “Multidimensional analysis of memory mechanisms”The 4th retreat was held at Amanohashidate in Miyazu, Kyoto Prefecture.。In addition to 7 domestic universities、USAMax Planck Florida Institute for Neuroscience (MPFI)、France Interdisciplinary Institute for Neuroscience (IINS)Many researchers and students from across the world gathered for three days of scientific discussion and exchange from October 23rd to 26th.。From Yuzaki Lab、Yuzuzaki、Keiko Matsuda、With an oral presentation by Thomas Chater、With graduate student Andressa、4Medical student (Narumi-kun, supervised by Dilina)、Mr. Iwasaki、Mr. Kanai、Tonoki-kun (supervised by Keiko Matsuda)、gave poster presentations respectively.。

Co-hosting the 175th Brain Club with Bio2QIt was held on October 22nd at。The speaker was Professor Peter Sheiffele of Biozentrum, University of Basel.、The title of the presentation was "Control of Visual Cortex Wiring and Molecular Programs by Spontaneous Neuronal Activity"。We have developed a new technology to comprehensively analyze the proteins that make up synapses and gene expression in the pre- and post-synaptic areas.、I listened with great interest to the latest research results on how specific synapse formation is controlled in response to spontaneous neural activity in the visual system.。

At the 37th Japan Glaucoma Society symposium held in Shizuoka, "Latest basic research aimed at restoring nerve function," Yuzaki gave a talk on glaucoma treatment by repairing retinal synapses using CPTX.。
University of Tokyo, Professor Megumi Honjo、Tokyo Medical Research Institute Takayuki Harada is the organizer。Other speakers are Dr. Akiko Sotozono, Tokyo Jikei Medical University、Tokyo Metropolitan Institute of Medical Science, Dr. Kazuhiko Namegata、It was Professor Shinichi Fukuda from the University of Tsukuba.。

Science Council of JapanPublic Symposium/34th Brain Century Symposiumwas held on Saturday, September 26th at the Science Council of Japan auditorium.。
The theme this time is “Brain and Generative AI”、The special lecture was titled "Brain and Artificial Intelligence - Two Intelligent Systems"、It was Professor Shunichi Amari, a specially appointed professor at Teikyo University Advanced Research Institute.。Next, “Understanding the Brain”、"Protect your brain"、"Creating a brain"、There were lectures on the latest research results from the four fields of "nurturing the brain"。Yuzaki is the chairperson of the Neuroscience Subcommittee of the Science Council of Japan, Committee on Basic Medicine.、Served as the opening greeting and moderator for the panel discussion.。
On-demand distribution will also be available at a later date.。

The dopamine synapse connector research project promoted by Yuzaki et al.、JST's Deep Tech Startup International Expansion Program (D-Global)was adopted by。After the kickoff meeting、A social gathering was held to celebrate the start of the project.。

Mr. Yamazaki (Tokyo University of Science)、The research results of Mr. Kakegawa (Gakushuin University) while he was a member of the Yuzaki laboratory are、Molecular Therapy .。
In this study、Two families with hereditary cerebellar ataxia caused by mutations in the CBLN1 gene, which plays an important role in synapse formation, were discovered.。further、We created mice with the same genetic mutation as the patient.、Abnormalities in CBLN1 impair synapse formation and function.、We have clarified the mechanism that causes cerebellar ataxia.。What is especially important is、The therapeutic effect was also obtained in adult mice that had already developed cerebellar ataxia.。By introducing the normal CBLN1 gene into cerebellar glial cells using an AAV vector,、Reduced synapses recover、It was also shown that the symptoms of cerebellar ataxia were significantly improved.。
This research、In addition to uncovering a new cause of hereditary cerebellar ataxia that was previously unknown.、This study demonstrates the possibility of improving neurological symptoms by rebuilding synapses even after the onset of symptoms.。It is expected that this will lead to the development of gene therapy for hereditary cerebellar ataxia in the future.。

Yuzaki gave a special lecture on September 15th at Nara Prefectural Medical University.。There was a lively question and answer session, which significantly extended the lecture time.。The audience includes high school and university juniors.、I also had a great time with my son's colleagues from his training days.。Unfortunately it was raining, but we were able to see the new school building and research building that matched the ancient capital.。(Dr. Saito, Physiologist, who planned the project)、Thank you)。