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Welcome to Yuzaki Lab
    Yuzaki Lab's (Department of Neurophysiology, Keio University School of Medicine) research theme is to elucidate "how neural activity and environmental changes induce memory and learning,、, 、and how they change the neural network itself ."。For details please Click here.
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We await the participation of motivated indivisuals。We will vigorously nurture young researchers who will lead the future of basic science.。
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2005

Analysis of GABA in the feedback signal through the system turtle retinal cone cells (View. Neurosci.)2005.12.31
Tatsukawa, T., Hirasawa, H., Kaneko, A. and Kaneda, M. GABA-mediated component in the feedback response of turtle retinal cones. View. Neurosci., 22:317-324, 2005.

 

Zinc is an endogenous substance of the signal system modifications rat retinal glycine receptors (J. Mol. Histol.)2005.12.31

Kaneda, M., Ishii, K., Akagi, T., Tastukawa, T. and Hashikawa, T. Endogenous zinc can be a modulator of glycinergic signaling pathway in the rat retina. J. Mol. Histol. 36: 179-185, 2005.

 

Cbln1 is essential for synapse formation and synaptic plasticity in the cerebellum (Nature Neurosci)2005.9.25

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Hirai, H., Pang, Z., How, D., Miyazaki, T., Li, L., Miura, E., Parris, J., Algae, Y., Watanabe, W., Yuzaki, M.*, Morgan, JI: Cbln1 is essential for synaptic integrity and plasticity in the cerebellum. Nature Neurosci., 8:1534-1541, 2005. (*co-corresponding author)
http://www.nature.com/neuro/journal/v8/n11/abs/nn1576.html

 

BDNF-dependent control of protein synthesis in dendrites by Hzf (PNAS)2005.9.25

Iijima T, Imai T, Kimura Y, Bernstein A, Okano HJ, Yuzaki M, Okano H. Hzf protein regulates dendritic localization and BDNF-induced translation of type1 Inositol 1,4,5-trisphosphate receptor mRNA. Proc. Natl. Acad. Sci. USA, 102:17190–17195, 2005.
http://www.pnas.org/cgi/content/full/102/47/17190

 

New molecular mechanisms of LTP induction in the cerebellum in the postsynaptic (PNAS)2005.9.25

Kakegawa, W., Yuzaki, M. A mechanism underlying AMPA receptor trafficking during cerebellar long-term potentiation. Proc. Natl. Acad. Sci. USA, 102:17846–17851, 2005.
http://www.pnas.org/cgi/content/full/102/49/17846

 

Delta II receptor expression during cerebellar LTD is phosphorylated by protein kinase C (Eur J Neurosci)2005.8.9

Kondo, T., Kakegawa, W., Yuzaki, M. Induction of long-term depression and phosphorylation of the delta2 glutamate receptor by protein kinase C in cerebellar slices. Eur. J. Neurosci., 22:1817-1820,2005.
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1460-9568.2005.04319.x

 

Structure and Function of the most N-terminal domain of the receptor AMPA (J Biol Chem)2005.5.25

Matsuda, S., Kamiya, Y., Yuzaki, M. Roles of the N-terminal domain on the functions and quaternary structure of the ionotropic glutamate receptor, J. Biol. Chem., 280:20021–20029, 2005.
http://www.jbc.org/cgi/content/full/280/20/20021

 

Molecular analysis of the function by transgenic rescue (invited review; Transgenic Res)2005.5.25

Yuzaki, M. Transgenic rescue for characterizing orphan receptors: a review of delta2 glutamate receptor, Transgenic Res., 14:117-121, 2005.
http://www.springerlink.com/content/r320761884175068/

 

GABA in the feedback component of the reaction in the retina (Vis Neurosci)2005.3.1

Tatsukawa, T., Hirasawa, H., Kaneko, A., Kaneda, M. GABA-mediated component in the feedback response of turtle retinal cones. View. Neurosci. 22:317-324, 2005.

 

Zn endogenous cholinergic signals to the modification of glycine in the retina (J Mol Histol)2005.3.1

Kaneda, M., Ishii, K., Akagi, T., Tatsukawa, T., Hashikawa, T. Endogenous zinc can be a modulator of glycinergic signaling pathway in the rat retina. J. Mol. Histol. 36:179-185, 2005.

 

Restoration of brain function due to epithelial cell-derived neural stem cell transplantation (Neurosci Res)2005.3.1

Uchida, K., Momiyama, T., Okano, H., Yuzaki, M., Koizumi, A., My, Y., Kawase, T. Potential functional neural repair with grafted neural stem cells of early embryonic neuroepithelial origin. Neurosci. Res., 52:276-86, 2005.
http://www.sciencedirect.com/science/journal/01680102

 

The function of glutamate receptor delta-2 binding site is not required (EMBO Rep)2005.1.9

Hirai, H., Miyazaki, T., Kakegawa, W., Matsuda, S., Mishina, M., Watanabe, M., Yuzaki, M. Rescue of abnormal phenotypes of the delta2 glutamate receptor-null mice by mutant delta2 transgenes, EMBO Report, 6: 90-95, 2005.
http://www.nature.com/embor/journal/v6/n1/abs/7400312.html