Engineered adhesion molecules drive synapse organization.
In Dylan Hale, Thomas C Südhof, Richard L Huganir
Proc Natl Acad Sci USA 120(3):e2215905120, 2023.

FYI:

Engineered synaptic tools reveal localized cAMP signaling in synapse assembly
--Richard Sando, Milan Lyndie Ho, Xinran Liu, Thomas C. Südhof
J Cell Biol (2022) 221 (2): e202109111.

2022Annual (54th) Naito Memorial Prize for Science Promotionwas awarded to Yuzuzaki。3The presentation ceremony was held at the Industrial Club of Japan on the 16th of the month.。
The award-winning research theme is "Elucidation of the molecular mechanisms that control functional and structural synaptic plasticity"。Thank you to the collaborators, Yuzu Lab's colleagues and OB。

34 days from 6th to 9th of the month、Okinawa Institute of Science and Technology Graduate University (OIST))Meeting after a long time atWorkshop “Nervous System Assembly”It has been made。Poster presentation + Flash talk by Oishi, a graduate student from Yuzaki Lab、Yuzuzaki gave a talk。Blessed with good weather, a lively discussion took place.。                                                                                       Tomi Yoshida of OIST was the organizer。

On November 10, 2018, Keio University launched the World Premier International Research Center Initiative (WPI).)Adopted as a base for、2The kick-off meeting was held on March 3rd.。(Human Biology x MicroBiome x Quantum computing = Bio2Q)As、Focusing on the Microbiome、How human homeostasis is controlled by mucosal epithelium, immunity, nerves, metabolism, etc.、A 10-year project that aims to elucidate using quantum computing with AI。Under Director Honda、Yuzuzaki as the representative of the neural control team、I will also participate as a special assistant to the center director.。

2022JSPS International Joint Research Acceleration Fund (International Leading Research) to “Multidimensional Analysis of Memory Mechanisms”–from nm to mesoscale/millisecond to day scale”.。Bordeaux Neuroscience Institute（Dr. Choquet）、Max Planck Florida Institute（Drs. Yasuda & Fitzpatrick) and Japan.。Represented by Professor Yasunori Hayashi of Kyoto University、At domestic bases of Keio University, NIG, Niigata University, and the University of Tokyo、Next 7 years (up to 10 years)、We will work on international exchange and development of young researchers, mainly postdocs and graduate students.。

For postdocs and graduate studentsSupport for short-term and long-term study abroadPlease spread the information so that you can watch it.。AlsoSupport for young researchers when they become independentYou can do it, so please make the most of your chance.。

Yuzaki gave a special lecture on January 21, 2023 at the 11th Neuro Conference Wakayama (Wakayama Medical University Kimiidera Campus)。Invited by Dr. Norimitsu Inoue, Department of Molecular Genetics, a leading expert in complement research。The photo is Professor Murai of the Department of Neurology, International University of Health and Welfare, another special lecturer.。

Core-to-core program symposium “Molecular Physiology of Neuronal Signaling” of the core-to-core program “Research Center for Interdisciplinary Neuronal Signaling” (Doshisha University, Free University of Berlin, IST, Austria, University of Copenhagen), Circuits and Behavior” January 12-14、Yuzu gave an invited talk at Doshisha University in Kyoto。

International Symposium from January 6th to January 9th, 2023 at Keio University Mita CampusNeurovascular Unit Conference 2023It has been made。Supported by the Japan-US Brain Research Cooperative Program、On the Japanese side, Prof. Hitoshi Nakahara, Department of Neurology, Keio University、On the US side, Mr. Ken Arai from MGH was the organizer.。Yuzuzaki gave a keynote speech。

Small molecules administered to adults、As a new technology that visualizes how and where in the brain it is distributed like a snapshot、We have developed a method for immobilizing small molecules using paraformaldehyde, which is often used in tissue fixation.。by this method、metabotropic glutamate receptor mGlu1、AMPA-type glutamate receptor、Succeeded in visualizing the localization pattern of dopamine receptors after ligand administration。This research was supported by ERATO/CREST.、In collaboration with Nagoya University Seichu Lab、published in Chemit was done。

Science Digest、Human Frontier Science Program (HFSP)is a new publication of。In HFSP-supported research、The most notable scientific achievements are highlighted。Commemorative first issue was published、We are the German Center for Neurodegenerative Diseases(DZNE)of Alexander Dityatev Laboratory、I was informed that the research I conducted with Dr. Radu Aricescu, Oxford University (at that time) has been published.。
HFSP home pagecan be read at。Also、excerpt isfrom hereavailable for download。

Goal 7 of the moonshot research and development project, "Understanding and application of intestinal bacterial action principle for extending healthy life expectancy" was adopted.、A kick-off meeting was held this time。Professor Kenya Honda is the project manager (PM))Is the、Yuzuzaki will participate as PM assistant and team leader of the "gut-brain linkage analysis team"。2022It is a research and development project for 6 years from FY 2019 (up to 9 years until FY 2030).。

Workshop 2022 was held to improve Presentation Skills。

Presentation skills for researchers、In addition to presenting research results and interacting with other researchers,、Returning research results to the general public、It is an essential technology when acquiring research funds。As an active brain science researcher,、Lectures and practical training were given by Professor George Augustine, who has a proven track record in teaching presentation methods.。
Graduate students belonging to Keio University Graduate School of Medicine, Graduate School of Pharmaceutical Sciences, and Graduate School of Science and Engineering、Young researchers participated。

This program is a WPI (Bio2Q)It is scheduled to be held as one of the joint graduate school programs (STaMP) in。

*Click here for Lecture videos→Open to those who belong to Keio University。

※※Lecture and Workshophere (photo)