Translation

Welcome to Yuzaki Lab

・柚﨑研は慶應義塾大学 ヒト生物学-微生物叢-量子計算研究センター(WPI-Bio2Q)に移動しました。

・中枢神経系に加えて、末梢・自律・腸管神経系でのシナプス形成機構に焦点をあて、神経系と多臓器の連関機構やその破綻による病態の解明と治療法の開発を目指します。

Past News

Journal Club

2019/7/8 Journal Club (Miura)

In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation

Margaret T. Davis, Ansel Hillmer, Sophie E. Holmes, Robert H. Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A. Angarita, Richard E. Carson, John H. Krystal, and Irina Esterlis

PNAS June 4, 2019 116 (23) 11490-11495

posted on 07/05/2019 9:39 PM

2019/7/1 Journal Club (Nozawa)

Hafner, A.-S., Donlin-Asp, P. G., Leitch, B., Herzog, E., & Schuman, E. M. (2019).

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments.

Science, 364(6441), eaau3644. https://doi.org/10.1126/science.aau3644

posted on 06/28/2019 5:29 PM

2019/6/17 Journal Club (Aimi)

Science. 2019 Apr 12;364(6436)

Ultrapotent chemogenetics for research and potential clinical applications.

Magnus CJ, Lee PH, Bonaventura J, Zemla R, Gomez JL, Ramirez MH, Hu X, Galvan A, Basu J, Michaelides M, Sternson SM.

PMID: 30872534

posted on 06/14/2019 6:58 PM

2019.6.10 Journal Club (Suyama)

Neuron. 2019;102:653–6.
The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits
Li MM, Madara JC, Steger JS, Krashes MJ, Balthasar N, Campbell JN, et al. Neuron. Cell Press; 2019.

Journal club by Shigetomo Suyama

posted on 06/10/2019 11:38 AM

2019.5.13 Journal Club (Bannai)

Cell Rep. 2019 Apr 16;27(3):658-665.e4. doi: 10.1016/j.celrep.2019.03.041.
Simultaneous Live Imaging of Multiple Endogenous Proteins Reveals a Mechanism for Alzheimer’s-Related Plasticity Impairment.
Cook SG, Goodell DJ, Restrepo S, Arnold DB, Bayer KU.

Journal club by Hiroko Bannai

posted on 04/22/2019 3:35 PM

2019/04/07 Journal Club (Yuzaki)

Orlandi C, Omori Y, Wang Y, Cao Y, Ueno A, Roux MJ, Condomitti G, de Wit J, Kanagawa M, Furukawa T, Martemyanov KA. Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors. Cell Rep. 2018 Oct 2;25(1):130-145.

Condomitti G, Wierda KD, Schroeder A, Rubio SE, Vennekens KM, Orlandi C, Martemyanov KA, Gounko NV, Savas JN, de Wit J. An Input-Specific Orphan Receptor GPR158-HSPG Interaction Organizes Hippocampal Mossy Fiber-CA3 Synapses. Neuron. 2018 Oct 10;100(1):201-215.

posted on 04/07/2019 3:00 PM

2019/3/18 Journal Club (Kono)

Cannabinoid CB1 receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior

posted on 03/16/2019 8:33 PM

2019/03/11 Journal Club (Kakegawa)

Fossati et al., EMBO Journal (2019) e99529

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and beta1-integrin.

posted on 03/01/2019 9:13 PM

2019/02/04 Journal Club (Motohashi)

Front. Behav. Neurosci., 14 June 2010 | https://doi.org/10.3389/fnbeh.2010.00029
Naoki Matsuo, Keizo Takao, Kazuo Nakanishi, Nobuyuki Yamasaki, Koichi Tanda and Tsuyoshi Miyakawa

posted on 02/04/2019 10:20 AM

2019/1/21 Journal club by Arai

Nature. 2018 Dec;564(7735):213-218
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.
Leroy F, Park J, Asok A, Brann DH, Meira T, Boyle LM, Buss EW, Kandel ER, Siegelbaum SA.

PMID: 30518859

posted on 01/20/2019 7:25 AM

2019/01/07 Journal Club (Yamasaki)

http://science.sciencemag.org/content/early/2018/12/12/science.aav1483.long#sec-11

 

posted on 01/04/2019 11:35 AM

2018/11/19 Journal Club (Ishida)

https://www.nature.com/articles/s41586-018-0633-x

posted on 11/16/2018 3:10 PM