Translation

Welcome to Yuzaki Lab
    慶應義塾大学医学部柚崎研(神経生理学)では「神経活動や環境の変化が、どのようにして記憶・学習を引き起こし、どのように神経回路網そのものを変化させるのか」というテーマに沿って研究を行っています。詳しくはこちら
Past News
Journal Club
Recruiting!
意欲あふれる方の参加を待っています。これからの基礎科学を担う若手研究者を積極的に育てていきます。
   医学部修士過程はこちら
   医学部博士課程はこちら
   連絡先はこちら

投稿者の記事一覧

2022/11/7 Journal Club (Nozawa)

Programmable RNA sensing for cell monitoring and manipulation

Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A Matthews, Michael Adoff, Weixin Zhong, Xu An, Michele Yeo, Christine Park, Xiaolu Yang, Bor-Shuen Wang, Derek G Southwell, Z Josh Huang.

Nature 2022 Oct;610(7933):713-721. doi: 10.1038/s41586-022-05280-1. Epub 2022 Oct 5.

PMID: 36198803

posted on 11/04/2022 2:48 PM

2022/02/12 Journal Club (Nozawa)

Stepwise synaptic plasticity events drive the early phase of memory consolidation

Goto A, Bota A, Miya K, Wang J, Tsukamoto S, Jiang X, Hirai D, Murayama M, Matsuda T, McHugh TJ, Nagai T, Hayashi Y.
Science. 2021 Nov 12;374(6569):857-863. doi: 10.1126/science.abj9195. Epub 2021 Nov 11.
PMID: 34762472

posted on 02/12/2022 4:10 PM

2021/05/17 Journal Club (Nozawa)

Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids allows access to masked epitopes in live neurons

Diogo Bessa-NetoAlexander Kuhlemann, Gerti Beliu, Valeria Pecoraro, Sören Doose, Natacha Retailleau, Nicolas Chevrier, David Perrais, Markus Sauer, and Daniel Choquet
bioRxiv, Posted February 28, 2021.

posted on 05/14/2021 8:25 PM

2020/8/30 Journal Club(Nozawa)

bioRxiv, posted August 21, 2020.
Astrocytic Neurexin-1 Orchestrates Functional Synapse Assembly
Justin H. Trotter, Zahra Dargaei, Markus Wöhr, Kif Liakath-Ali, Karthik Raju, Sofia Essayan-Perez, Amber Nabet, Xinran Liu, Thomas C. Südhof
doi: https://doi.org/10.1101/2020.08.21.262097

posted on 08/30/2020 12:02 PM

2020/02/29 Journal Club(Nozawa)

Neuron. 2019 Nov 20;104(4):693-710.e9. doi: 10.1016/j.neuron.2019.08.014. Epub 2019 Sep 23.
Distinct Nanoscale Calcium Channel and Synaptic Vesicle Topographies Contribute to the Diversity of Synaptic Function.
Rebola N, Reva M, Kirizs T, Szoboszlay M, Lőrincz A, Moneron G, Nusser Z, DiGregorio DA.

posted on 02/29/2020 12:28 PM

2019/7/1 Journal Club (Nozawa)

Hafner, A.-S., Donlin-Asp, P. G., Leitch, B., Herzog, E., & Schuman, E. M. (2019).

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments.

Science, 364(6441), eaau3644. https://doi.org/10.1126/science.aau3644

posted on 06/28/2019 5:29 PM

2018/08/31 Journal Club(Nozawa)

Graded control of climbing-fiber-mediated plasticity and learning by inhibition in the cerebellum.

Rowan MJM, Bonnan A, Zhang K, Amat SB, Kikuchi C, Taniguchi H, Augustine GJ, Christie JM.

Neuron. 2018 Aug 9. pii: S0896-6273(18)30598-1. doi: 10.1016/j.neuron.2018.07.024. [Epub ahead of print]

posted on 08/31/2018 2:00 PM

2018/1/15 Journal Club(Nozawa)

Neurexin controls plasticity of a mature, sexually dimorphic neuron.

Nature 553, 165–170 (11 January 2018)
doi:10.1038/nature25192

posted on 01/13/2018 12:47 PM

2017/06/12 Journal Club (Nozawa)

Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness.

Neuron. 2017 May 17;94(4):840-854.e7. doi: 10.1016/j.neuron.2017.04.021.

posted on 06/11/2017 7:44 PM

2016/12/12 Journal Club (Nozawa)

Bo Zhang and Thomas C. Südhof

J Neurosci. 2016 Aug 31;36(35):9070-83. doi: 10.1523/JNEUROSCI.1356-16.2016.

Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.

 

cf. Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

posted on 12/10/2016 4:48 PM

7/11/2016 Journal Club (Nozawa)

Feng Gao, Xiao Z Shen, Feng Jiang, Yongqiang Wu, Chunyu Han.

DNA-guided genome editing using the Natronobacterium gregoryi Argonaute

Nature Biotechnology 2016 May 2.

doi: 10.1038/nbt.3547. [Epub ahead of print]

 

posted on 07/08/2016 6:55 PM