Koda lecturer of paper is Publish to Eur J Neurosci、It was on the cover。Congrats。

Although the delta receptor is a molecule that controls the long-term depression (LTD) which is a basis course of motor learning in the cerebellum、It was so far unknown how the function to。In this paper、To deficient cerebellum the delta 2 receptor、By introducing a delta receptor with a viral vector、The LTD succeeded to be restored。

Interestingly、When the deficient C-terminus of the intracellular domain of Delta 2 receptor、That the LTD induction function of the delta 2 receptor is lost it was found。As a result、Delta 2 receptors、Rather than ionotropic glutamate receptor、Function as metabotropic receptors that transmit signals through the intracellular domain was suggested。

Iijima an assistant of the marriage celebration was conducted by Alice Garden。You happy!!

Joint research with RIKEN BSI FuruichiKen is now Accept the Journal of Neuroscience magazine。Kakegawa Assistant Professor has electrophysiological analysis of parallel fibers over Purkinje cells neurotransmission another Lobule of the cerebellum。

A paper by Associate Kakegawa J Physiol (London)Now in press in。Congrats。

This paper、By L7 promoter、By mating transgenic mice and delta 2 receptor null mutant mice expressing specific delta receptor in Purkinje cells、The recovery degree of various phenotypes of null mutant mouse thing was electrophysiological and morphological study。

Surprisingly、Not only normal delta 2 receptor、Delta 2 receptor mutated Q / R site to determine the Ca permeability in the channel pore also、It found that to recover most of the phenotype。From this it、Delta 2 receptor is now clear that the amino acid sequence does not function as a Ca channel but is expected to form a Ca ion transmission channel pore of。

Work on the function of Cbln family molecules of special research assistant Iijima、Eur J Neurosciにin pressに。Congrats。

Kameyama-kun of self-directed learning announcement of medical students was awarded the Excellence Award。Congrats。Kono's Hongo-kun of the research report also was very great。

To in press in the new book "The Glutamate Receptors" in the Review of Yuzusaki about the delta receptor The Humana Press。

First Papers is Accept in Eur J Neurosci of graduate doctoral second year Ishida's this classroom。In a systematic work on the involvement of MAPK in the cerebellum LTD expression、Unlike the hippocampus LTD that p38MAPK are involved、In the cerebellum LTD p42 / 44MAPK be involved、Article its action point showing that it is not a mGluR1 previously thought。Congrats。

Kakegawa assistant 2006 the Japan Neuroscience Society Award Winner。Congrats!

Matsuda (Keiko) assistant、Return from maternity leave。New delphilin isoforms (N-terminal extra with new PDZ domain) paper on becomes Accept to J Biol Chem during which。Congrats。

5Celebration meeting of 26 days Kakegawa assistant marriage month (and the second time bowling tournament)。You happy!

We were working together at Yuzusaki Research Institute in the United States St. Jude Children's Research Hospital era、Promotion from Hirai-san Kanazawa innovation brain science project research area assistant professor in Gunma nerve Department of Physiology Professor。Congratulations!。5Was a celebration meeting a month 19 days。