Excitatory neurotransmitter in our brain are borne by glutamate、Especially AMPA receptor is an important receptor that convey the fast neurotransmission。It is what the number of AMPA receptors in the postsynaptic changes in the long term、It is thought that the most fundamental processes of memory。So far about a change in the number of AMPA receptors、Or carried out by antibody staining in fixed specimens、Or it has been studied by expressing the exogenous AMPA receptor with a fluorescent probe。In this research、By developing an entirely new chemical labeling method、Endogenous AMPA receptors in the brain were visualized、We were able to observed over time the change。This achievement is the result of joint research by Kyoto University Ken Hamachi and yuzu 﨑研 that have been made with the support of the JST CREST。It was published in Nature Communication.。

Dr. Anis Contractor (Department of Physiology, FSM and Department of Neurobiology, WCAS Northwestern University) gave a talk at the 115th Brain Club on April 6th.  The title of the talk was “Life without Kainate Receptors: Insights from Kainate Receptor Knockout Mice.”

Dr. Jaewon Ko (Laboratory of Neural Circuits and Social Behaviours Department of Brain and Cognitive Sciences Daegu Gyeongbuk Institute of Science and Technology (DGIST), Korea) gave a talk at the 114th Brain Club on March 23rd. The title of the talk was “Molecular Principles of Neural Circuit Development: Synapse Organizers.”

It was published in "Japanese researchers who have appeared in the journal Science," the annual。From and this project is started is the appearance of the second time following in 2011。This booklet is誰でもダウンロードして読めますのでどうぞ。Thesis of Yuzusakiken is 44 pages。

The First group meeting of the new academic area, "dynamic control of brain function by scrap-and-build process" was carried out in March 6 to 8 days Karuizawa Prince Hotel。Diligently until late at night I stayed the Discussion was made to the lodge。

Axon's first clause (AIS) is a site that generates an action potential、Formed by Ankyrin G has been known to be controlled。But Ankyrin or G is given to how the integration was not well understood。Papers this time microtubule bridging molecules MTCL1 revealed that plays an essential role in the formation and maintenance of AIS isThis work has been published in EMBO J.it was done。Is the study of the Satake-san and Suzuki, professor of Yokohama City University。Yuzu In Nagasaki Institute is a joint research san and Miura Takeo has the help of intrauterine electroporation and organizations analysis。

In the new academic area "nerve Glycobiology" final symposium Suzuki Assistant Professor (Adjunct) was awarded the Best Poster Award。Congrats!

A new review on C1q family proteins “The C1q complement family of synaptic organizers: not just complementary.” has been published in Current Opinion in Neurobiology.

By introducing mRNA encoding the transcription factor、How to efficiently and rapidly differentiated from iPS cells into motor neuronsScientific Reportsにpublishit was done。This paper is the result of joint research with Hong teacher of the system Medicine。Also it was featured in such Nihon Keizai Shimbun。

 A reunion party of Keio Physiology Laboratories was held on February 11, 2017. A lecture was also given by Dr. Shibata,ja. See photo.

On February 3 and 6, Dr. Radu Aricescu, a visiting professor from Oxford University, gave two lectures on entitled “Introduction to Modern Structural Biology.”

A review on the delta glutamate receptors (wheels) “A GluD Coming-Of-Age Story (A GluD Coming-of-Age Story)” has been published in Trends in Neuroscience.