Translation

Welcome to Yuzaki Lab

・Yuzaki Laboratory has been relocated to the Center for Human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q.。

In addition to the central nervous system、focusing on synaptic formation mechanisms in the peripheral, autonomic and enteric nervous system、we aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop new treatments.。

Past News

Journal Club

2022/1/17 Journal club (Takasugi)

A brain-to-spinal sensorimotor loop for repetitive self-grooming.
Xie Z, Li D, Cheng X, Pei Q, Gu H, Tao T, Huang M, Shang C, Geng D, Zhao M, Liu A, Zhang C, Zhang F, Ma Y, High P.
Neuron.. 2021 Dec 15:S0896-6273(21)00989-2. doi: 10.1016/j.neuron.2021.11.028. Epub ahead of print.
PMID: 34932943.

posted on 01/17/2022 2:47 PM

2021/12/20 Journal Club (Kakegawa)

Gomez-Castro et al., Science (Article) 5 Nov 2021, Flight 374, Issue 6568

Convergence of adenosine and GABA signaling for synapse stabilization during development.

https://www.science.org/doi/10.1126/science.abk2055

posted on 12/18/2021 11:06 PM

2021/12/13 Journal Club (Aimi,zh-CN)

Nature. 2021 Oct;598(7881):489-494.
Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis
Mikihito Shibata, Kartik Pattabiraman, Sydney K Muchnik, Navjot Kaur, Yury M Morozov, Xiaoyang Cheng, Stephen G Waxman & Nenad Sestan
PMID: 34599306

※Related article in the same issue
Nature. 2021 Oct;598(7881):483-488.
Regulation of prefrontal patterning and connectivity by retinoic acid
Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa & Nenad Sestan
PMID: 34599305

posted on 12/10/2021 5:42 PM

2021/11/15 Journal Club(Ishikawa)

Temporal controls over inter-areal cortical projection neuron fate diversity (nature)

Esther Klingler, Ugo Tomasello, Julien Prados, Justus M. Kebschull,
Alessandro Contestabile, Gregorio L. Chickens, Sabine Fever, Antonio Santinha,Randal Platt, Daniel Huber, Alexandre Dayer, Camilla Bellone & Denis Jabaudon, Published online: 9 November 2021

posted on 11/12/2021 2:53 PM

2021/11/08 Journal Club (M. Yuzaki)

Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo
Taisuke Miyazaki, Megumi Morimoto-Tomita, Coralie Berthoux, Kotaro Konno, Yoav Noam, Tokiwa Yamasaki, Matthijs Verhage, Pablo E Castillo, Masahiko Watanabe, Susumu Tomita.
eLife 2021;10:e59613

posted on 11/08/2021 2:55 AM

2021/10/25 Journal Club (M. Itoh)

Synaptic correlates of associative fear memory in the lateral amygdala.

Choi DI, Kim J, Lee H, Kim JI, Sung Y, Choi JE, Venkat SJ, Park P, Jung H, Kaang BK.

Neuron.. 2021 Sep 1;109(17):2717-2726.e3. doi: 10.1016/j.neuron.2021.07.003.

Epub 2021 Aug 6. PMID: 34363751

 

posted on 10/24/2021 11:47 AM

2021/10/18 Journal club (Arai)

Nat Commun. 2021 Aug 23;12(1):5083.
AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions
Jake F Watson, Alexandra Pinggera, Hinze Ho, Ingo H Greger
PMID: 34426577 DOI: 10.1038/s41467-021-25281-4

posted on 10/17/2021 11:02 PM

Journal club, 2021-09-06, T. Yamasaki,,en,e3,,bg,j.neuron.2018.03.034,,en,Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors,,en,Regan MC,,en,Grant T,,en,McDaniel MJ,,en,Karakas E,,el,Zhang J,,zh-CN,Traynelis SF,,en,Grigorieff N,,af,Furukawa H,,en

Hi all.

I’d like to present this paper published in Neuron.

“Enhancing motor learning by increasing the stability of newly formed dendritic spines in the motor cortex.”

https://www.sciencedirect.com/science/article/abs/pii/S0896627321005742

posted on 09/03/2021 11:08 PM

2021/08/30 journal club (T.Imai)

Nat Neurosci. 2021 June;24(6):777-785. doi: 10.1038/s41593-021-00843-3. Epub 2021 Apr 29.

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation

Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S Ferreira, Florian Levet , Corey Butler 5, Jean-Baptiste Sibarita ,Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi

PMID: 33927400 DOI: 10.1038/s41593-021-00843-3

posted on 08/31/2021 5:58 PM

2021/8/16 Journal Club (Ishida,,en,Ian Schmitt et al.,,en,Thalamic amplification of cortical connectivity sustains attentional control,,en,www.nature.com/nature/journal/v545/n7653/pdf/nature22073.pdf,,en)

Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models: Neuron. (cell.com)

posted on 08/16/2021 9:59 AM

2121/7/19 Journal Club (Matsuda)

https://www.sciencedirect.com/science/article/pii/S0896627321001549

posted on 07/20/2021 4:18 PM

2021/7/12 Journal Club(Takeo)

Science. 2021 Jul 2;373(6550):77-81. doi: 10.1126/science.abf5273. PMID: 34210880

Astrocytes close the mouse critical period for visual plasticity

Jerome Ribot, Rachel Breton, Charles-Felix Calvo, Julien Moulard, Pascal Ezan, Jonathan Zapata, Kevin Samama, Matthew Moreau, Alexis-Pierre Bemelmans, Valentin Sabatet, Florent Dingli, Damarys Loew, Chantal Milleret, Pierre Billuart, Glenn Dallérac and Nathalie Rouach

posted on 07/09/2021 4:47 PM