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Welcome to Yuzaki Lab

・Yuzaki Laboratory has been relocated to the Center for Human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q.。

In addition to the central nervous system、focusing on synaptic formation mechanisms in the peripheral, autonomic and enteric nervous system、we aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop new treatments.。

Past News

Journal Club

2022/07/04 Journal Club (Kakegawa)

Cutando et al., Nature Neuroscience (2022) June 16 online

Cerebellar dopamine D2 receptors regulate social behaviors.

PMID: 35710984 DOI: 10.1038/s41593-022-01092-8

(If you cannot return due to the influence of the Okinawa typhoon、Including whether or not it is implemented、Please let consultation。)

posted on 07/02/2022 12:48 AM

2022/06/20 Journal Club (Yuzaki)

GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits
Simon Bossi 1, Dhanasak Dhanasobhon 2, Graham C R Ellis-Davies 3, Jimena Frontera 1, Marcel de Brito Van Velze 2, Joana Lourenço 2, Alvaro Murillo 4, Rafael Lujan 4, Married Mariano 1, Isabel Perez-Otano 5, Alberto Bacci 2, Daniela Popa 1, Pierre Paoletti 6, Nelson Rebola 7
Neuron. 2022 June 10;S0896-6273(22)00457-3.

doi: 10.1016/j.neuron.2022.05.016. ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder.

posted on 06/17/2022 10:25 AM

2022/06/13 Journal Club (A. Ishikawa)

Emergent reliability in sensory cortical coding and inter-area communication
Sadegh Ebrahimi 1 2 3 4, Jerome Lecoq 5 6 7 8, Oleg Rumyantsev 5 6 9, Tugce Tasci 5 6 10, Yanping Zhang 5 6 11, Cristina Irimia 5 6 7, Jane Li 5 7, Surya Ganguli 5 9,

2022 May;605(7911):713-721.
doi: 10.1038/s41586-022-04724-y. Epub 2022 May 19.

posted on 06/12/2022 11:48 PM

2022/05/30 Journal Club (M. Itoh)

Compartmentalized dendritic plasticity during associative learning.
of Aquinas S, Szonyi A, Mahn M, Krabbe S, Groundsman J, Luthi A.
Science. 2022 Apr 15;376(6590):eabf7052. doi: 10.1126/science.abf7052.
Epub 2022 Apr 15. PMID: 35420958

posted on 05/29/2022 1:18 PM

2022/5/16 Journal club (Arai)

Neuron.. 2022 May 4;110(9):1559-1572.e4. doi: 10.1016/j.neuron.2022.01.028. Epub 2022 Feb 17.

A direct lateral entorhinal cortex to hippocampal CA2 circuit conveys social information required for social memory

Jeffrey Lopez-Rojas, Christopher From The Sun, Felix Leroy, Eric R Kandel, Steven A Siegelbaum

PMID: 35180391

 

posted on 05/15/2022 11:13 PM

2022/05/09 Journal Club, T. Yamasaki,,en,e3,,bg,j.neuron.2018.03.034,,en,Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors,,en,Regan MC,,en,Grant T,,en,McDaniel MJ,,en,Karakas E,,el,Zhang J,,zh-CN,Traynelis SF,,en,Grigorieff N,,af,Furukawa H,,en

The preference for sugar over sweetener depends on a gut sensor cell

Buchanan and Bohorquez et al., Nat Neuroscie, 2022

https://www.nature.com/articles/s41593-021-00982-7#Sec11

PMID: 35027761

posted on 05/06/2022 1:57 PM

2022/5/2 Journal Club Matsuda

Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice

Neuron.
Available online 19 April 2022 In Press

doi.org/10.1016/j.neuron.2022.03.033

https://www-sciencedirect-com.kras.lib.keio.ac.jp/science/article/pii/S089662732200304X

posted on 04/30/2022 7:41 PM

2022/4/18 Journal Club(Takeo)

Sarah Cheng, Sarah Cheng, Sarah Cheng, Sarah Cheng, Sarah Cheng, Sarah Cheng, Sarah Cheng, Sarah Cheng

Sarah Cheng

Cell. 2022 Jan 20;185(2):311-327.Sarah Cheng. doi: 10.1016/Sarah Cheng.

PMID: 35063073

posted on 04/15/2022 3:19 PM

2022/3/14 Journal Club(Shiozaki)

ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder,1 ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder, ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder2022 Jan 20;S0896-6273(21)01090-4. doi: 10.1016/ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorderASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder.

posted on 03/13/2022 3:33 PM

2022/02/21 Journal Club (Dilina)

Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm

Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm, Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm. Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm, Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm, Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm. Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm

bioRxiv, Posted January 22, 2022.
https://Visualizing Synaptic Dopamine Efflux with a 2D Nanofilm

posted on 02/19/2022 11:08 PM

2022/02/12 Journal Club (Nozawa)

Stepwise synaptic plasticity events drive the early phase of memory consolidation

Stepwise synaptic plasticity events drive the early phase of memory consolidation, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Wang J, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Jiang X, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Stepwise synaptic plasticity events drive the early phase of memory consolidation, Nagai T, Hayashi Y.
Science. 2021 Nov 12;374(6569):857-863. doi: 10.1126/Stepwise synaptic plasticity events drive the early phase of memory consolidation. Epub 2021 Nov 11.
PMID: 34762472

posted on 02/12/2022 4:10 PM

2022/1/24 Journal Club (Suyama)

Reverse-translational identification of a cerebellar satiation network

Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network , Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network , Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network, Reverse-translational identification of a cerebellar satiation network

Nature. 2021 Dec;600(7888):269-273. doi: 10.1038/Reverse-translational identification of a cerebellar satiation network. Epub 2021 Nov 17.

posted on 01/24/2022 7:50 AM