Translation

Welcome to Yuzaki Lab

・Yuzaki Laboratory has been relocated to the Center for Human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q.。

In addition to the central nervous system、focusing on synaptic formation mechanisms in the peripheral, autonomic and enteric nervous system、we aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop new treatments.。

Past News

Journal Club

2023/03/06 Journal Club (Arai)

Nat Commun. 2023 Jan 16;14(1):244.

mGluR5 is transiently confined in perisynaptic nanodomains to shape synaptic function
Nicky Scheefhals, Manon Westra, Harold D MacGillavry

doi: 10.1038/s41467-022-35680-w.

PMID: 36646691

posted on 03/05/2023 9:48 PM

2023/02/20 Journal club, Tokiwa Yamasaki

2023/02/20JC will introduce the following papers。

https://www.sciencedirect.com/science/article/pii/S0896627322008686?via%3Dihub

Subunit composition, molecular environment, and activation of native TRPC channels encoded by theirinteractomes

Kollewe et al.Neuron., 2022

 

Thank you。

posted on 02/20/2023 11:11 AM

2Month 13 Journal Club Matsuda

https://www.sciencedirect.com/science/article/pii/S009286742201577X#undfig1

posted on 02/13/2023 12:18 PM

2023/1/23 Journal Club (L. Ohgaki)

Dendrite Self-Avoidance Requires Cell-Autonomous Slit/Robo Signaling in Cerebellar Purkinje Cells

Daniela. Gibson, Stephen Tymansky, Rachel C. Yuan, Haiwen C. Leung, Julie L. Lefebvre, Joshua R. It's not, Alain Che ́ dotal, and Le Ma

https://doi.org/10.1016/j.neuron.2014.01.009

posted on 01/20/2023 1:02 PM

2022/12/12 Journal Club (Takeo)

Synaptic pruning through glial synapse engulfment upon motor learning

Yosuke M.. Morizawa, Mami Matsumoto, Yuka Nakashima, Narumi Endo, Tomomi Aida, Hiroshi Ishikane, Kaoru Beppu, Satoru Morito, Hitoshi Inada, Noriko Osumi, Eiji Shigetomi, Schuichi Koizumi, guangyang, Hirokazu Hirai, Kohichi Tanaka, Kenji F.. Tanaka, Nobuhiko Ohno, Yugo Fukazawa & Ko Matsui., Nature Neuroscience, Nov;25(11):1458-1469. (2022)

doi: 10.1038/s41593-022-01184-5.

PMID: 36319770

posted on 12/09/2022 4:46 PM

2022/11/14 Journal Club (Dilina)

The gut-to-brain axis for toxin-induced defensive responses

Zhiyong Xie, Xianying Zhang, Miao Zhao, …, Fengchao Wang, Congping Shang, Peng Cao

Cell 185, 1–19; Published online. 2022 Oct 25;

PMID: 36323317 DOI: 10.1016/j.cell.2022.10.001

posted on 11/11/2022 2:32 PM

2022/11/7 Journal Club (Nozawa)

Programmable RNA sensing for cell monitoring and manipulation

Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A Matthews, Michael Adoff, Weixin Zhong, Xu An, Michelle Yeo, Christine Park, Xiaolu Yang, Bor-Shuen Wang, Derek G Southwell, Z Josh Huang.

Nature 2022 Oct;610(7933):713-721. doi: 10.1038/s41586-022-05280-1. Epub 2022 Oct 5.

PMID: 36198803

posted on 11/04/2022 2:48 PM

2022/10/31 Journal Club (Oishi)

Neuron., Volume 110, Issue 9, 2022, Pages 1532-1546.e4.

Differential dendritic integration of long-range inputs in association cortex via subcellular changes in synaptic AMPA-to-NMDA receptor ratio

Mathieu Lafourcade, Marie-Sophie H. van der Goes, Dimitra Vardalaki, Norma J. Brown, Jakob Voigts, Dae Hee Yun, Minyoung E. Kim, Taeyun Ku, Mark T. Harnett

1Department of Brain & Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
2Department of Brain & Cognitive Sciences, Picower Institute for Learning & Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

doi: 10.1016/j.neuron.2022.01.025

posted on 10/27/2022 1:29 PM

2022/9/5 Journal Club (Suyma)

Nature 609: 374–380. Published online 13 July 2022
Dopamine subsystems that track internal states.
Grove JCR, Gray LA, The Holy Medina N, Sivakumar N, Ahn JS, Body TV, Berke JD, Kreitzer AC, Knight ZA
DOI: 10.1038/s41586-022-04954-0

posted on 09/05/2022 9:38 AM

2022/8/15 Journal Club (L. Ohgaki)

Developmental Cell. Posted July 11, 2022.

Dendtites use mechanosensitive channels to proofread ligand-mediated neurite extension during morphogenesis.

Li Tao, Sean Coakley, Rebecca Shi, Kang Shen

doi: https://doi.org/10.1016/j.devcel.2022.05.019

07/22/2022 6:36 PM | Journal Club

posted on 08/15/2022 2:11 PM

2022/07/25 Journal Club (Aimi.T)

bioRxiv.  Posted May 29, 2022.

Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking

V. C. Wong, P.R. Houlihan, H. Liu, D. They passed by, M.C. DeSantis, Z. Liu, and E. C. O’Shea

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20147

doi: https://doi.org/10.1101/2022.05.29.493906

This article is a preprint and has not been certified by peer review.

※Paper printing"not recommended"

posted on 07/22/2022 6:36 PM

2022/07/11 Journal Club

The following treatises will be introduced at JC next Monday.。Which L, et al., Neuron.. 2022 Mar 2;110(5):809-823.e5.
Glutamate in primary afferents is required for itch transmission.
PMID: 34986325 doi: 10.1016/j.neuron.2021.12.007. Epub 2022 Jan 4. Thank you.。

https://pubmed.ncbi.nlm.nih.gov/34986325/

posted on 07/11/2022 8:40 AM