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Welcome to Yuzaki Lab

・Yuzaki Laboratory has been relocated to the Center for Human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q.。

In addition to the central nervous system、focusing on synaptic formation mechanisms in the peripheral, autonomic and enteric nervous system、we aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop new treatments.。

Past News

Journal Club

2020/3/16 Journal Club (Motohashi)

Sci Rep. 2019 Aug 9;9(1):11571. doi: 10.1038/s41598-019-47964-1.

Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization.

https://www.nature.com/articles/s41598-019-47964-1.pdf

posted on 03/14/2020 3:21 PM

2020/03/09 Journal club(Takatsuto)

Neuron.. 105 (1), 46-59.e3

2020 Jan 8

mGlu 2 and mGlu 3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects

Max E Joffe, Chiaki In Santiago, Kendra H Oliver, James Maksymetz, Nicholas A Harris, Julie L Engers, Craig W Lindsley, Danny G Winder, P Jeffrey Conn.

posted on 03/06/2020 7:44 PM

2020/02/29 Journal Club(Nozawa)

Neuron.. 2019 Nov 20;104(4):693-710.e9,,ar,j.neuron.2017.06.029,,en,Chai H,,en,Diaz-Castro B,,es,Shigetomi E,,ja,And Monte,,it,Octeau JC,,en,Cohn W,,en,Rajendran PS,,en,Vondriska TM,,ar,Whitelegge JP,,en,Coppola G,,es,Khakh BS,,bg,Neural Circuit-Specialized Astrocytes,,en,Transcriptomic,,en,Proteomic,,en,Morphological,,en,and Functional Evidence,,en,See also Nature,,en,NEWS,,en,VIEWS,,en. doi: 10.1016/j.neuron.2019.08.014. Epub 2019 Sep 23.
Distinct Nanoscale Calcium Channel and Synaptic Vesicle Topographies Contribute to the Diversity of Synaptic Function.
N rool, Reva M, T Kirizsán, Szoboszlay M, The Lorincz, Moneron G, nuzzles Z, DiGregorio DA.

posted on 02/29/2020 12:28 PM

2020/02/10 Journal club (Suyama)

Two genetically, anatomically and functionally distinct cell types segregate across anteroposterior axis of paraventricular thalamus.

Claire Gao, Yan Leng, Jun Ma, Victoria Rooke, Shakira Rodriguez-Gonzalez, Charu Ramakrishnan, Karl Deisseroth & Mario A. Penzo
Nature Neuroscience volume 23, pages217–228(2020)

posted on 02/10/2020 12:04 AM

2020/02/03 Journal club (Aimi,zh-CN)

bioRxiv. Posted January 06, 2020.

Mesophasic organization of GABAA receptors in hippocampal inhibitory synapse

Yun-Tao Liu, Chang-Lu Tao, Xiaokang Zhang, Lei Qi, Rong Sun, Pak-Ming Lau, Hong Zhou, Guo-Qiang Bi

doi: https://doi.org/10.1101/2020.01.06.895425

This article is a preprint and has not been certified by peer review.

posted on 01/30/2020 8:53 PM

JC on,en 2020.1.20 by Ishikawa

Neuron.. 2019 Dec 26. <HTML><HEAD><meta http-equiv="content-type" content="text/html;charset=utf-8"> <TITLE>302 Moved</TITLE></HEAD><BODY> <H1>302 Moved</H1> The document has moved <A HREF="http://ipv4.google.com/sorry/IndexRedirect?continue=http://translate.google.com/translate_a/t?client=a&q=pii&q=S0896-6273&q=j.neuron.2015.05.013&q=elegans+Punctin+Clusters+GABAA+Receptors+via&q=Neuroligin&q=Binding+and+UNC-40%2FDCC+Recruitment&tl=en&sl=auto&amp;q=CGMSBMu9aZ8Y2OjZqwUiGQDxp4NLW_vuiJQA0cSRRi_F4WdisaRqdCQ">here</A>. </BODY></HTML> : S0896-6273(19)31047-5. doi: 10.1016/j.neuron.2019.12.005. [Epub ahead of print]

Cortical Synaptic AMPA Receptor Plasticity during Motor Learning.

Roth RH1, Cudmore RH2, Tan HL1, Hong I1, Zhang Y3, Distracted RL4.

posted on 01/20/2020 9:12 AM

2019/12/02 Journal Club (M. Itoh)

2019/12/02 Journal Club (M. Itoh)

Science 2019 Oct 11

Shisa7 is a GABAA receptor auxiliary subunit controlling benzodiazepine actions.

Han W, Li J, Pelkey ​​KA, Pandey S, Chen X, Wang YX, Wu K, Ge L, Li T,

Castellano D, Liu C, Wu LG, Petralia RS, Lynch JW, McBain CJ, Lu W.

https://www.ncbi.nlm.nih.gov/pubmed/31601770

posted on 11/29/2019 9:52 PM

2019/11/18 Journal Club(Shikanai,ja)

2019/11/18 Journal Club(Shikanai,ja)

Axoglial Adhesion by Cadm4 Regulates CNS Myelination.

https://www.sciencedirect.com/science/article/pii/S0896627318310419?via%3Dihub

posted on 11/15/2019 7:22 PM

journal club on 11/11, 2019 In. Arai

Neuron.. 2019 Sep 19

An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity.

swivel J, With Boudkkazi, Torches B et al.

 

PMID: 31604597

 

posted on 11/09/2019 7:07 PM

Journal Club Tokiwa Yamasaki (2019-08-26)

https://www.sciencedirect.com/science/article/pii/S0896627319303472?via=ihub

posted on 08/14/2019 1:01 PM

2019/8/5 Journal Club (Ishida,,en,Ian Schmitt et al.,,en,Thalamic amplification of cortical connectivity sustains attentional control,,en,www.nature.com/nature/journal/v545/n7653/pdf/nature22073.pdf,,en)

https://science.sciencemag.org/content/364/6436/eaat8078.long

posted on 08/01/2019 10:03 AM

2019On July 22 Journal Club Matsuda

https://www.nature.com/articles/s41593-019-0419-y

posted on 07/22/2019 12:19 AM