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Welcome to Yuzaki Lab

・Yuzaki Laboratory has been relocated to the Center for Human biology - Microbiota - Quantum Computational Research (Keio University)WPI-Bio2Q.。

In addition to the central nervous system、focusing on synaptic formation mechanisms in the peripheral, autonomic and enteric nervous system、we aim to clarify the linkage between the nervous system and multiple organs, and the pathology caused by its failure, and to develop new treatments.。

Past News

Journal Club

2021/01/18 journal club (T.Imai)

https://pubmed.ncbi.nlm.nih.gov/33208945/

posted on 01/18/2021 11:36 AM

2020December 21,  Journal Club (Matsuda)

https://www.biorxiv.org/content/10.1101/2020.11.25.395806v1.full#F11

The HSPG Syndecan is a core organizer of cholinergic synapses in C. elegans
From Jean-Louis Bessereau Lab.

posted on 12/21/2020 12:00 AM

2020/12/14 Journal Club (Takano)

NATURE COMMUNICATIONS | (2020)11:5171 |

Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer

Nuno Apóstolo 1,2, Samuel N. Smukowski3, Jeroen Vanderlinden 1.2, Giuseppe Condomitti1,2, Vasily Rybakin4, Jolijn ten Bos 1,2, Laura Trobiani5, Sybren Portuguese1,2, Kristel M. Friends1.2, Natalia V. Gounko 1,2,6, Davide Comoletti 5.7, Keimpe D. Wierda1,2, Jeffrey N. Savas 3 & Joris de Wit 1,2

1 VIB Center for Brain & Disease Research, Herestraat 49, 3000 Leuven, Belgium. 2 KU Leuven, Department of Neurosciences, Leuven Brain Institute, Herestraat 49, 3000 Leuven, Belgium. 3 Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, THE 60611, USA.
4 Immunobiology, REGA Institute, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium. 5 School of Biological Sciences, Victoria University of Wellington, Wellington 6140, New Zealand. 6 Electron Microscopy Platform & VIB BioImaging Core, Herestraat 49, 3000 Leuven, Belgium. 7 Child Health Institute of New Jersey, and Departments of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA

posted on 12/14/2020 12:00 PM

2020/12/7 Review club (Aimi.T)

Structural Plasticity of Axon in Adult

Please check the PDF file in Review club folder.

posted on 12/07/2020 10:28 AM

2020/11/9 Journal Club (Takeo)

Neuron.,
Available online 14 September 2020

Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism

Lucas Cheadle, Samuel A Rivera, …, Michael E Greenberg

PMID: 32931754
DOI: 10.1016/j.neuron.2020.08.002

posted on 11/06/2020 4:29 PM

2020/11/2 Journal Club(Shiozaki)

Nature Neuroscience, July 13, 2020

The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development

Qifei Cong, Breeanne M. Soteros, Mackenna Wollet, Jun Hee Kim, Crazy Ming Sia

https://doi.org/10.1038/s41593-020-0672-0

DOI:10.1038/s41593-020-0672-0

posted on 11/01/2020 11:11 AM

2020/10/19 Journal Club (L. Ohgaki)

Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer’s disease model mouse line

L Russo-Savage, VKS Rao, BA Eipper, RE Mains

Neurobiology of Aging, posted July 14th, 2020.

https://doi.org/10.1016/j.neurobiolaging.2020.07.006

posted on 10/19/2020 11:53 AM

2020/09/07 Journal Club (Dilina Tuerde)

Neuromodulator Signaling Bidirectionally Controls VesicleNumbers in Human Synapses.

Christopher Patzke, Marisa M. Brockmann, Jinye Dai, …, Thomas C. Your ̈ dhof.

posted on 09/03/2020 1:06 PM

2020/8/30 Journal Club(Nozawa)

bioRxiv, posted August 21, 2020.
Astrocytic Neurexin-1 Orchestrates Functional Synapse Assembly
Justin H. Trotter, Zahra Dargaei, Markus Wöhr, Kif Liakath-Ali, Karthik Raju, Sofia Essayan-Perez, Amber Nabet, Xinran Liu, Thomas C. Südhof
doi: https://doi.org/10.1101/2020.08.21.262097

posted on 08/30/2020 12:02 PM

2020/08/03 Review Club (In. Arai)

Membrane Surface Trafficking of Glutamate Receptors

posted on 08/03/2020 4:10 PM

2020/07/20 Journal Club (Suyama.S)

Pancreatic Islets Communicate With the Brain via Vagal Sensory Neurons
Madina Makhmutova, Jonathan Weitz, Alejandro Tamayo, Elizabeth Pereira, Joana Almaça, Rayner Rodriguez-Diaz, Alejandro Caicedo
bioRxiv 780395; doi: https://doi.org/10.1101/780395

posted on 07/20/2020 7:02 AM

2020/07/13 Journal Club (A.Ishikawa)

Context-Dependent Decision Making in a Premotor Circuit
Zheng Wu , Ashok Litwin-Kumar, Philip Shamash , Alexei Taylor, Richard Axel , Michael N Shadlen
Neuron.(2020) 106, 316-328
PMID: 32105611 DOI: 10.1016/j.neuron.2020.01.034

posted on 07/12/2020 6:57 PM