Assistant Professor Takano received the Young Investigator Award from Keio University School of Medicine in the 4th year of Reiwa.。Congratulations!

GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits
Simon Bossi 1, Dhanasak Dhanasobhon 2, Graham C R Ellis-Davies 3, Jimena Frontera 1, Marcel de Brito Van Velze 2, Joana Lourenço 2, Alvaro Murillo 4, Rafael Lujan 4, Married Mariano 1, Isabel Perez-Otano 5, Alberto Bacci 2, Daniela Popa 1, Pierre Paoletti 6, Nelson Rebola 7
Neuron. 2022 June 10;S0896-6273(22)00457-3.

doi: 10.1016/j.neuron.2022.05.016. ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder.

To understand how neural circuits in the brain work、There is a need for technology that selectively activates glutamate receptors, which are neurotransmitter receptors that control memory and learning.。In this research、While maintaining the original glutamate response ability、Developed a mutant glutamate receptor (metabolized type) activated by an artificial compound。We created mice that actually expressed this artificial glutamate receptor in a specific cell type.、It was shown that the administration of artificial compounds activates metabotropic glutamate receptors in a cell-type selective manner.。It is expected that the understanding of neural circuits will be accelerated by using this new technology "coordination chemogenetics method".。This research was supported by ERATO / CREST, Nagoya University Kiyonaka Lab.、This is a joint research with Kyoto University Hamaji Lab.。Click here for the paper

A translation of the 3rd edition of the original Brainbook "Mieru Brain" has been published.。It is a general book that explains the basic structure and function of the brain in an easy-to-understand manner with CG, illustrations and photographs.。It is a general book that explains the basic structure and function of the brain in an easy-to-understand manner with CG, illustrations and photographs.。It is a general book that explains the basic structure and function of the brain in an easy-to-understand manner with CG, illustrations and photographs.。

Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"、Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"、 School of Medicine, Keio UniversityPermalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"。Permalink that is delivering "Study of Brain Studies"Permalink that is delivering "Study of Brain Studies"Please spread the information so that you can watch it.。

—

Fromthe President of the Japan Neuroscience SocietyGreetings at the beginning of the year2022。Let's all do our best this year, too!

12/8/2021, we held our 146th Brain Club and(welcomed Dr. Shigeki Watanabe of the Department of Cell Biology, Johns Hopkins University School of Medicine as the speaker。His talk was titled "Mechanisms of Synaptic Transmission."、He talked about the latest endocytosis mechanism at the presynaptic mechanism using the quick freezing method.。This time, the online seminar was held over 2 days, across the time difference of 14 hours.。(The snapshot after the personal interviews the day after the seminar)。

Dr. Takeo's review "Purkinje Cell Dendrites: The Time-Tested Icon in Histologyhas been published in the book "Cerebellum as a CNS hub" from Springer.。This review summarizes the results of the research on、dendrite development in neurons and its molecular mechanism to the date, Purkinje cells as a model、including Dr. Takeo's own work.。

Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo
Taisuke Miyazaki, Megumi Morimoto-Tomita, Coralie Berthoux, Kotaro Konno, Yoav Noam, Tokiwa Yamasaki, Matthijs Verhage, Pablo E Castillo, Masahiko Watanabe, Susumu Tomita.
eLife 2021;10:e59613

The 145th Brain Club was held with Dr. Kenichi Oki, Graduate School of Medicine, The University of Tokyo, Department of Integrated Physiology.。Titled "Mouse Vision / Monkey Vision"、Using the latest large-scale Ca imaging technology and tracing technology、He talked about the differences in visual information processing pathways from the retina to the higher visual cortex.。Mouse is a mouse、At the same time different from non-human primates in many ways、I learned the common points as the calculation principle.。This time as well, it was a hybrid seminar at Zoom at the same time as the face-to-face meeting.。

Assistant Professor Tetsuya Takano was selected as a third-year member in the JST PRESTO "Cell Interactions in Multicellular Systems and Their Dynamics" area (Yoshiko Takahashi Research Supervisor).。Congratulations!

The 144th Brain Club Seminar, which had been postponed for a year and a half from February 2020 due to the influence of COVID-19, was held.。The talk was titled "human-specific program that controls the development and evolution of the cerebral cortex" by Professor Ikuo Suzuki of the Graduate School of Science, the University of Tokyo.。

In addition to face-to-face lectures given in ample space and under infection-protection settings、it was a hybrid event with real-time streaming via Zoom.。
Both face-to-face and Zoom sessions were lively with questions and answers、We all enjoyed the Brain Club after a long absence。(We took off our masks only when taking this picture. We held our breaths, then。）