Muscle fibers are created by the fusion of myoblasts。Fusion of myoblasts happened even during muscle regeneration after damage, not only during development、It has been strictly controlled。We've discovered as a molecule to control the strengthening and pruning of climbing fibers of the cerebellum so far BAI3 is、Although the muscle fibers to be involved in the fusion of myoblasts had been shown so far、The detailed molecular mechanism was not well understood。In this paper、C1qL4 suppresses the BAI3、Stabilin-2 has revealed that temporally and spatially controlled fusion of myoblasts by activating (→ paper is here.）。Synapse formation is C1qL1-BAI3 in the cerebellum、In the muscle it is extremely interesting that C1qL4-BAI3 to control the muscle formation。As a joint research with Canada's Jean-François Côté laboratory、Conference and Kakegawa, Associate Professor of short-term come the Viviane Tran's a graduate student was indebted to Keio。

10/26/2018 1:25 PM | What's New