The 170th Brain Club was held on September 3, 2025, co-hosted with WPI-BIo2Q. This time, Dr. Yasuda Ryoheio (Max Planck Florida Institute for Neuroscience and Scientific Director) was invited as the lecturer.。The theme is "Decoding Synaptic Signaling Dynamics Underlying Plasticity"is。Behavioral Time Scale Plasticity (BTSP) is、It has attracted attention as synaptic plasticity that occurs on time scales (in seconds) related to individual-level learning.、The molecular mechanism is unknown。Dr. Yasuda and colleagues explored this problem using improved Ca2+/calmodulin-dependent kinase II (CaMKII) sensors.、10-100 seconds after BTSP induction、Delayed CaMKII activation in the dendrites was found to occur stocastically.、It was discovered that IP3-dependent intracellular Ca2+ release is involved in this phenomenon。It was an extremely interesting story that explored the individual-level learning mechanisms.。

09/05/2025 2:10 PM | What's New